Stopping weight-loss medications like Ozempic and Wegovy can lead to significant health risks. A new study shows that most people who stop taking semaglutide regain about two-thirds of the weight they lost and experience worsened health markers, like higher blood pressure and cholesterol.
These drugs, which mimic a hormone that controls appetite, are used by about 12% of U.S. adults, though many stop due to high costs or achieving their weight-loss goals. Despite their success in treating obesity and diabetes, stopping them may increase cardiovascular risks. Researchers suggest long-term use might be necessary to maintain the benefits.
While some users face severe side effects, such as nausea and stomach issues, the growing use of semaglutide has contributed to a decrease in national obesity rates. With high discontinuation rates, experts urge further research on the long-term effects of stopping these medications.